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DeCS
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Descriptor English:
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BTB-POZ Domain
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Descriptor Spanish:
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Dominio BTB-POZ
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Descriptor Portuguese:
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Domínio BTB-POZ
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Synonyms English:
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BTB (POZ) Domain
BTB Domain
BTB Domains
BTB POZ Domain
BTB-POZ Domains
Broad Complex, Tramtrack and Bric a Brac Domain
Broad-Complex, Tramtrack and Bric a Brac Domain
POZ Domain
POZ Domains
POxvirus and Zinc Finger Domain
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Tree Number:
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G02.111.570.820.709.275.750.500.343
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Definition English:
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A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56744
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Unique Identifier:
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D000071757
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Occurrence in VHL:
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Similar:
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DeCS
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